منابع مشابه
Evaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملA Review on Medicinal Plants Used in Animal Models and Clinical Trials concerning Drug Addiction
Addiction to drugs, such as heroin, cocaine and alcohol, exacts great human and financial costs on society. Various evidence-based pharmacological and psychosocial interventions are currently used in the treatment of drug addiction but they do not produce adequate therapeutic benefits in every patient. Further, barriers such as financial cost, lack of availability, or perceptions of existing tr...
متن کاملEvidence Based Medicine: Clinical Trials
Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...
متن کاملValidation of Instruments for Assessing Drug Safety Management During the Conduction of Clinical Trials
Background The management of drug safety with the collection of reliable safety data during the conduction of clinical trials conduct is essential for the registry and marketing of products. The systematic evaluation of this process, based on objective measures, requires the application of quality instruments. This study was aimed to design and validate eight instruments through the components ...
متن کاملthe importance of clinical trials in drug development
while preclinical research answers basic questions about a drug’s safety, it is not a substitute for studies of ways the drug will interact with the human body. “clinical research” refers to studies, or trials, that are done in people 1,2. as the developers design the clinical study, they will consider what they want to accomplish for each of the different clinical research phases and begin the...
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ژورنال
عنوان ژورنال: Nature
سال: 2012
ISSN: 0028-0836,1476-4687
DOI: 10.1038/481250a